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Association of plasma tau with mortality and long-term neurocognitive impairment (NCI) and children with cerebral malaria (CM) and severe malarial anemia (SMA), according to study findings published in JAMA Network Open. Children younger than 5 years were evaluated with the Mullen Scales of Early Learning, the Early Childhood Vigilance Test, and the Color Object Association Test. Children aged at least 5 years were assessed at enrollment and follow-up. The objective of the current study was to determine whether plasma tau can be a proxy marker of NCI after CM and SMA to limit the use of lumbar punctures to obtain CSF biomarkers.

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Plasma tau, which indicates injury to neuronal axons, is higher among children with cerebral malaria (CM) and severe malarial anemia (SMA), according to study findings published in JAMA Network Open. Children aged at least 5 years were assessed at enrollment and follow-up. Association of plasma tau with mortality and long-term neurocognitive impairment in survivors of pediatric cerebral malaria (CM) and severe malarial anemia (SMA), according to the researchers. Plasma tau, which indicates injury to neuronal axons, is higher among children with cerebral malaria and severe malarial anemia (SMA), according to actonel online canada the researchers.

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